Tudományos közlemények

2022

  • Menyhárt Á, Frank R, Farkas AE, Süle Z, Varga VÉ, Nyúl-Tóth Á, Meiller A, Ivánkovits-Kiss O, Lemale CL, Szabó Í, Tóth R, Zölei-Szénási D, Woitzik J, Marinesco S, Krizbai IA, Bari F, Dreier JP, Farkas E.Malignant astrocyte swelling and impaired glutamate clearance drive the expansion of injurious spreading depolarization foci.J Cereb Blood Flow Metab. 2022 Apr;42(4):584-599. doi: 10.1177/0271678X211040056.
    Open access
  • Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L. Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties. Int J Pharm. 2022 Mar 9:121653. doi: 10.1016/j.ijpharm.2022.121653
    Open access
  • Andrew RD, Hartings JA, Ayata C, Brennan KC, Dawson-Scully KD, Farkas E, Herreras O, Kirov SA, Müller M, Ollen-Bittle N, Reiffurth C, Revah O, Robertson RM, Shuttleworth CW, Ullah G, Dreier JP. The Critical Role of Spreading Depolarizations in Early Brain Injury: Consensus and Contention. Neurocrit Care. 2022 Mar 7. doi: 10.1007/s12028-021-01431-w
    Open access
  • Császár E, Lénárt N, Cserép C, Környei Z, Fekete R, Pósfai B, Balázsfi D, Hangya B, Schwarcz AD, Szabadits E, Szöllősi D, Szigeti K, Máthé D, West BL, Sviatkó K, Brás AR, Mariani JC, Kliewer A, Lenkei Z, Hricisák L, Benyó Z, Baranyi M, Sperlágh B, Menyhárt Á, Farkas E, Dénes Á. Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions. J Exp Med. 2022 Mar 7;219(3):e20211071. doi: 10.1084/jem.20211071.
    Open access
  • Andrew RD, Farkas E, Hartings JA, Brennan KC, Herreras O, Müller M, Kirov SA, Ayata C, Ollen-Bittle N, Reiffurth C, Revah O, Robertson RM, Dawson-Scully KD, Ullah G, Dreier JP. Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization. Neurocrit Care. 2022 Feb 22. doi: 10.1007/s12028-021-01429-4.
    Open access
  • Nunes C, Singh P, Mazidi Z, Murphy C, Bourguignon A, Wellens S, Chandrasekaran V, Ghosh S, Zana M, Pamies D, Thomas A, Verfaillie C, Culot M, Dinnyes A, Hardy B, Wilmes A, Jennings P, Grillari R, Grillari J, Zurich MG, Exner T. An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat. Toxicol In Vitro. 2022 Feb 16:105333. doi: 10.1016/j.tiv.2022.105333
    Open access
  • Szabo M, Lajkó N, Dulka K, Szatmári I, Fülöp F, Mihály A, Vécsei L, Gulya K. Kynurenic Acid and Its Analog SZR104 Exhibit Strong Antiinflammatory Effects and Alter the Intracellular Distribution and Methylation Patterns of H3 Histones in Immunochallenged Microglia-Enriched Cultures of Newborn Rat Brains. International Journal of Molecular Sciences. 2022; 23(3):1079. doi: 10.3390/ijms23031079
    Open access
  • Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A. Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements. International Journal of Molecular Sciences. 2022; 23(2):855. doi:10.3390/ijms23020855
    Open access
  • Francistiová L, Vörös K, Lovász Zs, Dinnyés A, and Kobolák J. Detection and Functional Evaluation of the P2X7 Receptor in HiPSC Derived Neurons and Microglia-Like Cells. Frontiers in Molecular Neuroscience 14, no. January (2022): 1–16. doi: 10.3389/fnmol.2021.793769.
    Open access

2021

  • Menyhárt Á, Varga DP, M Tóth O, Makra P, Bari F, Farkas E. Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex. Neurocrit Care. 2021 Dec 2. doi: 10.1007/s12028-021-01393-z. 
    Open access
  • Horánszky A, Becker JL, Zana M, Ferguson-Smith AC, Dinnyés A. Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons From iPSC and Mouse Models. Genes. 2021; 12(11):1704. doi: 10.3390/genes12111704. 
    Open access
  • Rubini E, Baijens IMM, Horánszky A, Schoenmakers S, Sinclair KD, Zana M, Dinnyés A, Steegers-Theunissen RPM, Rousian M. Maternal One-Carbon Metabolism during the Periconceptional Period and Human Foetal Brain Growth: A Systematic Review. Genes (Basel). 2021 Oct 17;12(10):1634. doi: 10.3390/genes12101634. 
    Open access
  • Lamberto F, Peral-Sanchez I, Muenthaisong S, Zana M, Willaime-Morawek S, Dinnyés A. Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes. Genes (Basel). 2021 Sep 30;12(10):1564. doi: 10.3390/genes12101564.
    Open access
  • Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ádám A, Sipos P, Farkas E, Bari F, Janovák L. The Effect of Molecular Weight on the Solubility Properties of Biocompatible Poly(ethylene succinate) Polyester. Polymers (Basel). 2021 Aug 15;13(16):2725. doi: 10.3390/polym13162725.
    Open access
  • Francistiová L, Klepe A, Curley G, Gulya K, Dinnyés A, Filkor K. Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain. Front. Immunol., 2021 Aug 13. doi.org/10.3389/fimmu.2021.730088.
    Open access
  • Szabó Í, Varga VÉ, Dvorácskó S, Farkas AE, Körmöczi T, Berkecz R, Kecskés S, Menyhárt Á, Frank R, Hantosi D, Cozzi NV, Frecska E, Tömböly C, Krizbai IA, Bari F, Farkas E. N,N-Dimethyltryptamine attenuates spreading depolarization and restrains neurodegeneration by sigma-1 receptor activation in the ischemic rat brain. Neuropharmacology. 2021 Jul 1;192:108612. doi: 10.1016/j.neuropharm.2021.108612.
    Open access
  • Pansri P, Phanthong P, Suthprasertporn N, Kitiyanant Y, Tubsuwan A, Dinnyes A, Kobolak J, Kitiyanant N. Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells. PeerJ. 2021 May 12;9:e11388. doi: 10.7717/peerj.11388. eCollection 2021.
    Open access
  • Frank R, Bari F, Menyhárt Á, Farkas E. Comparative analysis of spreading depolarizations in brain slices exposed to osmotic or metabolic stress. BMC Neurosci. 2021 May 3;22(1):33. doi: 10.1186/s12868-021-00637-0.
    Open access
  • Dulka K, Szabo M, Lajkó N, Belecz I, Hoyk Z, Gulya K. Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains. Int J Mol Sci. 2021 Mar 26;22(7):3412. doi: 10.3390/ijms22073412.
    Open access
  • Tóth R, Farkas AE, Krizbai IA, Makra P, Bari F, Farkas E, Menyhárt Á. Astrocyte Ca2+ Waves and Subsequent Non-Synchronized Ca2+ Oscillations Coincide with Arteriole Diameter Changes in Response to Spreading Depolarization. Int J Mol Sci. 2021 Mar 26;22(7):3442. doi: 10.3390/ijms22073442.
    Open access
  • Wang X, Li M, Zhang X, Li Y, He G, Dinnyés A, Sun Q, Xu W. CYP11A1 Upregulation Leads to Trophoblast Oxidative Stress and Fetal Neurodevelopmental Toxicity That can be Rescued by Vitamin D. Front Mol Biosci. 2021 Feb 15;7:608447. doi: 10.3389/fmolb.2020.608447. eCollection 2020.
    Open access
  • Dulka K, Nacsa K, Lajkó N, Gulya K. Quantitative morphometric and cell-type-specific population analysis of microglia-enriched cultures subcloned to high purity from newborn rat brains. IBRO Neurosci Rep. 2021 Feb 6;10:119-129. doi: 10.1016/j.ibneur.2021.01.007. eCollection 2021 Jun.
    Open access